SYMTUZA

Peak

darunavir, cobicistat, emtricitabine, and tenofovir alafenamide

NDAORALTABLET
Approved
Jul 2018
Lifecycle
Peak
Competitive Pressure
0/100
Clinical Trials
3

Mechanism of Action

Cytochrome P450 3A Inhibitors

Pharmacologic Class:

Cytochrome P450 3A Inhibitor

Clinical Trials (3)

NCT05463783Phase 4Unknown

Effect of Biktarvy & Symtuza on microRNAs in HIV and Correlation With Weight Gain

Started Mar 2023
30 enrolled
HIV InfectionsObesity
NCT04388904Phase 4Completed

Rapid Reinitiation of a Single Tablet Antiretroviral Therapy Using Symtuza® in HIV-1 Infected Treatment-Experienced Patients Off Therapy. (ReSTART)

Started Sep 2021
75 enrolled
HIV-1-infection
NCT04240210Phase 4Terminated

Integrase Regimen Switch to Symtuza to Increase Tolerability/Adherence (SYMita)

Started Sep 2019
1 enrolled
Human Immunodeficiency Virus

Loss of Exclusivity

LOE Date
Jul 19, 2038
150 months away
Patent Expiry
Jul 19, 2038

Patent Records (5)

Patent #ExpiryTypeUse Code
7700645
Dec 26, 2026
SubstanceProduct
8148374
Sep 3, 2029
SubstanceProduct
U-2365
8754065
Aug 15, 2032
SubstanceProduct
U-2765
9296769
Aug 15, 2032
SubstanceProduct
U-2765
10039718
Oct 6, 2032
Product