NDAORALSUSPENSION
Approved
Jan 1983
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
2/8 — Basic
SULFATRIM (sulfamethoxazole and trimethoprim) by Inpharmus is cytochrome p450 2c9 inhibitors [moa]. First approved in 1983.
Drug data last refreshed 11h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
SULFATRIM is a fixed-dose combination of sulfamethoxazole and trimethoprim, a synergistic sulfonamide antimicrobial approved in 1983 for oral suspension delivery. It works by inhibiting cytochrome P450 2C9 and disrupting bacterial folate synthesis, making it effective against a broad spectrum of bacterial infections. The dual mechanism provides superior bactericidal activity compared to monotherapy.
LOE Approaching
As LOE approaches, the brand team is likely consolidating and transitioning to generic management mode; headcount and budget typically contract in this phase.
Mechanism of Action
Cytochrome P450 2C9 Inhibitors
Pharmacologic Class:
Sulfonamide Antimicrobial
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
SULFATRIM career opportunities are limited; roles focus on generic cost optimization, payer negotiation, and supply management rather than brand building or clinical advancement. Professionals joining this asset should expect mature-market responsibilities with limited growth trajectory.
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.