SULFAMETHOXAZOLE AND TRIMETHOPRIM AND PHENAZOPYRIDINE HYDROCHLORIDE
LOE Approachingphenazopyridine hydrochloride; sulfamethoxazole; trimethoprim
NDAORALTABLET
Approved
Jun 2001
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
2/8 — Basic
SULFAMETHOXAZOLE AND TRIMETHOPRIM AND PHENAZOPYRIDINE HYDROCHLORIDE (phenazopyridine hydrochloride; sulfamethoxazole; trimethoprim) is clinical pharmacology phenazopyridine hydrochloride is excreted in the urine where it exerts a topical analgesic effect on the mucosa of the urinary tract. First approved in 2001.
Drug data last refreshed 12m ago · AI intelligence enriched 3w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
A fixed-dose combination tablet containing sulfamethoxazole, trimethoprim, and phenazopyridine hydrochloride for oral use. Sulfamethoxazole and trimethoprim work synergistically as a bacteriostatic antibiotic, while phenazopyridine provides topical analgesic relief to the urinary tract mucosa. This combination addresses both infection treatment and symptomatic relief in urinary tract infections.
LOE Approaching
Product approaching loss of exclusivity with moderate competitive pressure (30%), indicating a brand team focused on defending market share and optimizing profitability in a consolidating segment.
Mechanism of Action
CLINICAL PHARMACOLOGY Phenazopyridine hydrochloride is excreted in the urine where it exerts a topical analgesic effect on the mucosa of the urinary tract. This action helps to relieve pain, burning, urgency and frequency. The precise mechanism of action is unknown. PHARMACOKINETICS The…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
Working on this product offers limited external career momentum given LOE-approaching status and zero current linked job postings, but provides solid experience in defensive marketing, generic competition strategy, and fixed-dose combination optimization. Ideal for professionals seeking to develop expertise in portfolio rationalization and cost-focused commercial execution.
Brand Manager
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
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