SULFAMETHOXAZOLE AND TRIMETHOPRIM AND PHENAZOPYRIDINE HYDROCHLORIDE
LOE Approachingphenazopyridine hydrochloride; sulfamethoxazole; trimethoprim
NDAORALTABLET
Approved
Jun 2001
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
2/8 — Basic
SULFAMETHOXAZOLE AND TRIMETHOPRIM AND PHENAZOPYRIDINE HYDROCHLORIDE (phenazopyridine hydrochloride; sulfamethoxazole; trimethoprim) is clinical pharmacology phenazopyridine hydrochloride is excreted in the urine where it exerts a topical analgesic effect on the mucosa of the urinary tract. First approved in 2001.
Drug data last refreshed 2h ago · AI intelligence enriched 1mo ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
A fixed-dose oral combination tablet containing sulfamethoxazole, trimethoprim, and phenazopyridine hydrochloride used to treat urinary tract infections. The sulfonamide-trimethoprim components provide bactericidal activity against gram-positive and gram-negative organisms, while phenazopyridine acts as a topical urinary analgesic to relieve dysuria symptoms. The precise mechanism of phenazopyridine's analgesic action is unknown, but it is rapidly excreted in the urine where it localizes to the urinary mucosa.
LOE Approaching
Product approaching loss of exclusivity with moderate competitive pressure (30) indicates a team focused on defending market share and managing decline rather than growth initiatives.
Mechanism of Action
CLINICAL PHARMACOLOGY Phenazopyridine hydrochloride is excreted in the urine where it exerts a topical analgesic effect on the mucosa of the urinary tract. This action helps to relieve pain, burning, urgency and frequency. The precise mechanism of action is unknown. PHARMACOKINETICS The…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
Zero linked job openings reflect the product's mature, declining lifecycle stage with minimal hiring activity. Career opportunities on this product are limited to defensive commercial roles focused on market share retention, pricing strategy, and managed transition to generic competition.
Brand Manager
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
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