NDANASALSPRAY, METERED
Approved
Mar 1994
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
1
Data completeness
3/8 — Basic
STIMATE (NEEDS NO REFRIGERATION) (desmopressin acetate) by Ferring Pharmaceuticals is acetate's primary pharmacodynamic action involves its binding to vasopressin 2 (v2) receptors. First approved in 1994.
Drug data last refreshed 3d ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
STIMATE is a metered nasal spray formulation of desmopressin acetate, a synthetic vasopressin analog approved in 1994 for treating nocturia. The drug works by binding to V2 receptors in the kidney's collecting ducts, increasing water reabsorption and reducing urine production. It is distinguished by a room-temperature stable formulation that requires no refrigeration, improving patient convenience and compliance.
LOE Approaching
As an LOE-approaching product with moderate competitive pressure (30), the STIMATE brand faces contraction; commercial teams should expect smaller reimbursement and field organizations, with roles shifting toward managed care and patient retention strategies.
Mechanism of Action
acetate's primary pharmacodynamic action involves its binding to vasopressin 2 (V2) receptors. V2 receptors are primarily located in the distal convoluted tubule and collecting ducts of the nephron in the kidneys. These receptors play a crucial role in regulating water reabsorption and urine…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (1)
Desmopressin Acetate 0.2 mg Tablets, Fasting
Started Jul 2003
48 enrolled
Healthy
Career Relevance
Working on STIMATE offers exposure to portfolio management, global commercialization, and managed-care negotiation within a large, established pharmaceutical organization. However, the LOE-approaching lifecycle limits advancement potential and team growth; career value lies in crisis management, cost optimization, and transition planning skills.
Manager
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.