NDANASALSPRAY, METERED
Approved
May 2010
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
4
Data completeness
4/8 — Partial
SPRIX (ketorolac tromethamine) by Fresenius Kabi is clinical pharmacology pharmacodynamics ketorolac tromethamine is a nonsteroidal anti-inflammatory drug (nsaid) that exhibits analgesic activity in animal models. First approved in 2010.
Drug data last refreshed 3d ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
SPRIX is a nasal spray formulation of ketorolac tromethamine, a nonsteroidal anti-inflammatory drug (NSAID) that inhibits prostaglandin synthetase to provide analgesic and anti-inflammatory effects. It is indicated for moderate to severe acute pain including postoperative pain, low back pain, and ocular indications such as allergic conjunctivitis and post-operative anterior chamber inflammation. The S-enantiomer of ketorolac is responsible for therapeutic activity, with peak analgesic effect occurring within 2-3 hours.
$0.002BPart D
LOE ApproachingDeclining
Product is in LOE-approaching phase with minimal Part D spending and declining claims, indicating small-scale commercial teams and limited growth opportunities.
Mechanism of Action
CLINICAL PHARMACOLOGY Pharmacodynamics Ketorolac tromethamine is a nonsteroidal anti-inflammatory drug (NSAID) that exhibits analgesic activity in animal models. The mechanism of action of ketorolac, like that of other NSAIDs, is not completely understood but may be related to prostaglandin…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.