NDAORALCONCENTRATE
Approved
Nov 1957
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
1
Data completeness
2/8 — Basic
Drug data last refreshed 9h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
SPARINE (Promazine Hydrochloride) is an oral concentrate antipsychotic approved in 1957 for psychiatric indications. It is a first-generation phenothiazine that works through dopamine antagonism in the central nervous system. This legacy agent has a long clinical history but limited current utilization.
LOE Approaching
This legacy product faces significant generic competition (30% competitive pressure) with minimal active commercial infrastructure, indicating limited team expansion opportunities.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (1)
Assessment of Intra-subject Variability in the Bioavailability of Chlorpromazine Hydrochloride
Started Nov 2016
20 enrolled
Anti-PsychoticManagement of Manifestations of Psychotic DisordersTreatment of Schizophrenia+6 more
Career Relevance
Working on SPARINE offers limited career upside given its LOE-approaching status and minimal commercial investment. This role suits professionals seeking stable, low-intensity work in legacy product stewardship rather than growth-oriented career advancement.
Brand Manager (legacy product management)
Worked on SPARINE at Thayer Medical? Share your interview experience or compensation data (+7 days Pro)
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.