NDAORALCONCENTRATE
Approved
Nov 1957
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
1
Data completeness
2/8 — Basic
Drug data last refreshed 3d ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
SPARINE (promazine hydrochloride) is a first-generation antipsychotic approved in 1957 for schizophrenia, psychotic disorders, bipolar disorder, and off-label use in nausea, vomiting, hiccups, and anxiety. It is an oral concentrate formulation that works as a dopamine antagonist, though its exact mechanism of action is not fully characterized in modern pharmacological terms.
LOE Approaching
This product is in late-stage lifecycle with minimal commercial growth trajectory; team focus is likely on maintenance, compliance, and managed decline rather than expansion.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (1)
Assessment of Intra-subject Variability in the Bioavailability of Chlorpromazine Hydrochloride
Started Nov 2016
20 enrolled
Anti-PsychoticManagement of Manifestations of Psychotic DisordersTreatment of Schizophrenia+6 more
Career Relevance
Working on SPARINE offers limited career growth due to its mature, declining lifecycle and commodity-like market status. Roles are primarily transactional—focused on managed care, pricing, and distribution rather than innovation, launches, or market expansion.
Brand Manager
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.