NDAORALCONCENTRATE
Approved
Nov 1957
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
1
Data completeness
2/8 — Basic
Drug data last refreshed 3h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
SPARINE (promazine hydrochloride) is an oral concentrate antipsychotic belonging to the phenothiazine class, approved in 1957 for management of psychotic disorders. It works by blocking dopamine receptors in the central nervous system to reduce psychotic symptoms. The drug is typically used in patients requiring antipsychotic therapy, though it has largely been superseded by newer agents.
LOE Approaching
With lifecycle status approaching loss of exclusivity and minimal linked job activity, this brand operates with a small, maintenance-focused commercial team likely concentrated in specialty distribution and formulary management.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (1)
Assessment of Intra-subject Variability in the Bioavailability of Chlorpromazine Hydrochloride
Started Nov 2016
20 enrolled
Anti-PsychoticManagement of Manifestations of Psychotic DisordersTreatment of Schizophrenia+6 more
Career Relevance
Working on SPARINE offers limited career growth potential; roles are primarily maintenance-oriented, focused on regulatory compliance, generic competition management, and institutional channel support. This assignment is best suited to early-career professionals seeking foundational experience in legacy product management or compliance specialists managing mature asset portfolios.
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.