NDATOPICALAEROSOL, FOAM
Approved
Oct 2010
Lifecycle
LOE Approaching
Competitive Pressure
15/100
Clinical Trials
9
Data completeness
6/8 — Strong
SORILUX (calcipotriene) by Molecular Devices is clinical pharmacology in humans, the natural supply of vitamin d depends mainly on exposure to the ultraviolet rays of the sun for conversion of 7-dehydrocholesterol to vitamin d 3 (cholecalciferol) in the skin. Approved for psoriasis. First approved in 2010.
Drug data last refreshed 19h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
SORILUX is a topical vitamin D analog foam formulation of calcipotriene approved for psoriasis and acne vulgaris. It works by mimicking the active form of vitamin D (calcitriol), regulating skin cell proliferation and differentiation to reduce inflammatory plaques. Approximately 6% of the applied dose is systemically absorbed, with rapid metabolism to inactive metabolites.
$0.351MPart D
LOE Approaching2.0 years to LOEProduct is approaching loss of exclusivity with minimal Medicare spending, suggesting a small, declining commercial team focused on managed care and dermatology channels.
Mechanism of Action
CLINICAL PHARMACOLOGY In humans, the natural supply of vitamin D depends mainly on exposure to the ultraviolet rays of the sun for conversion of 7-dehydrocholesterol to vitamin D 3 (cholecalciferol) in the skin. Calcipotriene is a synthetic analog of vitamin D 3 . Clinical studies with…
Pharmacologic Class:
Vitamin D Analog
Indications (1)
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.