NDAINJECTIONINJECTABLE
Approved
May 1959
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
3/8 — Basic
SOLU-MEDROL (methylprednisolone sodium succinate) by Pfizer is clinical pharmacology glucocorticoids, naturally occurring and synthetic, are adrenocortical steroids that are readily absorbed from the gastrointestinal tract. First approved in 1959.
Drug data last refreshed 2d ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
SOLU-MEDROL (methylprednisolone sodium succinate) is a potent synthetic glucocorticoid administered via injection for rapid anti-inflammatory and immunosuppressive effects. It is indicated for acute myeloid leukemia and acute lymphoblastic leukemia, where it modulates immune response and reduces inflammation. The drug achieves demonstrable effects within one hour of IV injection with nearly complete excretion within 12 hours, requiring redosing every 4–6 hours for sustained therapeutic levels.
$4,000Part D
LOE ApproachingThis legacy product approaching loss of exclusivity with minimal Part D spending ($4K, 36 claims in 2023) signals a declining asset with limited commercial upside and likely compressed team size.
Mechanism of Action
CLINICAL PHARMACOLOGY Glucocorticoids, naturally occurring and synthetic, are adrenocortical steroids that are readily absorbed from the gastrointestinal tract. Naturally occurring glucocorticoids (hydrocortisone and cortisone), which also have salt-retaining properties, are used as replacement…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.