NDAINJECTIONINJECTABLE
Approved
May 1959
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
3/8 — Basic
SOLU-MEDROL (methylprednisolone sodium succinate) by Pfizer is clinical pharmacology glucocorticoids, naturally occurring and synthetic, are adrenocortical steroids that are readily absorbed from the gastrointestinal tract. First approved in 1959.
Drug data last refreshed 2h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
SOLU-MEDROL is a potent synthetic glucocorticoid (methylprednisolone sodium succinate) administered via injection for rapid anti-inflammatory and immunosuppressive effects. It is used across multiple organ systems to treat inflammatory and immune-mediated disorders, with onset of action within one hour and near-complete excretion within 12 hours. The drug's mechanism relies on profound metabolic effects and immune modulation rather than salt retention, distinguishing it from earlier corticosteroids.
$0.004BPart D
LOE ApproachingProduct approaching loss of exclusivity with minimal Part D utilization signals mature, stable franchise with reduced commercial team expansion opportunity.
Mechanism of Action
CLINICAL PHARMACOLOGY Glucocorticoids, naturally occurring and synthetic, are adrenocortical steroids that are readily absorbed from the gastrointestinal tract. Naturally occurring glucocorticoids (hydrocortisone and cortisone), which also have salt-retaining properties, are used as replacement…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.