NDAINJECTIONINJECTABLE
Approved
Apr 1955
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
3/8 — Basic
SOLU-CORTEF (hydrocortisone sodium succinate) by Pfizer is clinical pharmacology glucocorticoids, naturally occurring and synthetic, are adrenocortical steroids that are readily absorbed from the gastrointestinal tract. First approved in 1955.
Drug data last refreshed 3h ago · AI intelligence enriched 3d ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
SOLU-CORTEF is an intravenous/intramuscular injectable formulation of hydrocortisone sodium succinate, a rapid-acting glucocorticoid with potent anti-inflammatory and immunosuppressive properties. It is used to treat acute adrenocortical insufficiency, severe inflammatory conditions, and shock states requiring immediate high-dose corticosteroid intervention. The water-soluble sodium succinate ester enables rapid IV administration and achieves detectable therapeutic effects within one hour.
$0.674MPart D
LOE ApproachingAs a legacy product approaching loss of exclusivity, the brand team is likely in optimization mode with focus on cost management and hospital formulary retention rather than growth investment.
Mechanism of Action
CLINICAL PHARMACOLOGY Glucocorticoids, naturally occurring and synthetic, are adrenocortical steroids that are readily absorbed from the gastrointestinal tract. Naturally occurring glucocorticoids (hydrocortisone and cortisone), which also have salt-retaining properties, are used as replacement…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.