NDAOPHTHALMICSOLUTION/DROPS
Approved
Jul 1946
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
3/8 — Basic
SODIUM SULAMYD (sulfacetamide sodium) by Merck & Co. is clinical pharmacology the most widely accepted mechanism of action of sulfonamides is the woods-fildes theory, which is based on the fact that sulfonamides act as competitive antagonists to para-aminobenzoic acid (paba), an essential component for bacterial growth. Approved for the topical control of acne vulgaris, acne rosacea, seborrheic dermatitis. First approved in 1946.
Drug data last refreshed 11h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Sodium Sulamyd (sulfacetamide sodium) is a sulfonamide antibiotic available as an ophthalmic solution for topical control of bacterial infections and inflammatory skin conditions. It works by competitively antagonizing para-aminobenzoic acid (PABA), an essential component for bacterial growth, and may inhibit Propionibacterium acnes growth. The drug is indicated for acne vulgaris, acne rosacea, and seborrheic dermatitis.
LOE Approaching
Product is approaching loss of exclusivity with moderate competitive pressure (30), suggesting a mature, defensive franchise likely managed by a lean, efficiency-focused team.
Mechanism of Action
CLINICAL PHARMACOLOGY The most widely accepted mechanism of action of sulfonamides is the Woods-Fildes theory, which is based on the fact that sulfonamides act as competitive antagonists to para-aminobenzoic acid (PABA), an essential component for bacterial growth. While absorption through intact…
Indications (3)
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.