NDAORALTABLET
Approved
Aug 1962
Lifecycle
Post-LOE
Competitive Pressure
35/100
Data completeness
3/8 — Basic
SKELAXIN (metaxalone) by Pfizer is metaxalone's mechanism of action has not been fully characterized, but may be related to its sedative properties. First approved in 1962.
Drug data last refreshed Yesterday · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
SKELAXIN (metaxalone) is an oral skeletal muscle relaxant approved in 1962 for the treatment of muscle pain and stiffness associated with acute musculoskeletal conditions. Its mechanism of action is not fully characterized but is believed to relate to sedative properties rather than direct action on muscle fibers. It is administered as an oral tablet and represents a mature, well-established therapeutic option in the muscle relaxant class.
Post-LOEPost-LOE
Post-LOE stage with moderate competitive pressure (35/100) indicates a stable but declining franchise requiring defensive commercial strategies and focused resource allocation.
Mechanism of Action
Metaxalone's mechanism of action has not been fully characterized, but may be related to its sedative properties. Metaxalone has no direct action on the contractile mechanism of striated muscle, the motor end plate, or the nerve fiber.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Why This Matters for Your Career
Patent cliff in less than a year — expect lifecycle management and generic defense hiring
Worked on SKELAXIN at Pfizer? Share your interview experience or compensation data (+7 days Pro)
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.