SINEMET

LOE Approaching

carbidopa and levodopa

NDAORALTABLETPriority Review
Approved
May 1975
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
4

Mechanism of Action

DOPA Decarboxylase Inhibitors

Pharmacologic Class:

Aromatic Amino Acid

Clinical Trials (4)

NCT01533116Phase 1Completed

Effect of BIA 9-1067 at Steady-state on the Pharmacokinetics of Levodopa/Carbidopa and Levodopa/Benserazide

Started Mar 2009
NCT00460954N/ACompleted

A Multiple-Dose Study of Sinemet® CR (Carbidopa/Levodopa) in Healthy Subjects

Started Jun 2007
20 enrolled
Parkinson's Disease
NCT00139880Phase 3Completed

A Single Center, Randomized, Double-blind, Crossover Pilot Trial Comparing the Onset of Action of Parcopa™ With Sinemet® in Subjects With Stable Parkinson's Disease

Started Jun 2005
Parkinson's Disease
NCT00174239Phase 4Terminated

Study Of Cabaser and Sinemet CR For The Treatment Of Nighttime Symptoms Associated With Parkinson's Disease.

Started Jul 2004
220 enrolled
Parkinson Disease