NDAINJECTIONINJECTABLE
Approved
Mar 2006
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
2/8 — Basic
SEPTOCAINE (articaine hydrochloride; epinephrine bitartrate) by Pfizer is anesthetic. First approved in 2006.
Drug data last refreshed 6h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
SEPTOCAINE is a local anesthetic combining articaine hydrochloride with epinephrine bitartrate, administered via injection for regional anesthesia. It blocks nerve impulse generation and conduction while the epinephrine component acts as a vasoconstrictor to prolong anesthetic effect by slowing systemic absorption. The drug is used primarily in dental and oral surgical procedures requiring local anesthesia.
LOE Approaching
As LOE approaches, expect contraction in brand support and transition focus toward generic transition strategy and cost management rather than growth initiatives.
Mechanism of Action
anesthetic. Local anesthetics block the generation and conduction of nerve impulses, presumably by increasing the threshold for electrical excitation in the nerve, by slowing the propagation of the nerve impulse, and by reducing the rate of rise of the action potential. In general, the progression…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
Working on SEPTOCAINE offers limited career growth given the product's approaching LOE and modest linked job count; however, it provides stable experience in specialty pharmaceutical commercialization and dental/oral care markets. Career advancement is constrained by mature product lifecycle, making it suitable for consolidation roles or stepping stones to higher-growth therapeutic areas.
Brand Manager
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.