NDAINJECTIONINJECTABLE
Approved
Mar 2006
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
2/8 — Basic
SEPTOCAINE (articaine hydrochloride; epinephrine bitartrate) by Pfizer is anesthetic. First approved in 2006.
Drug data last refreshed 14h ago · AI intelligence enriched 4d ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Septocaine is a local anesthetic combining articaine hydrochloride with epinephrine bitartrate, administered by injection for regional anesthesia. It blocks nerve impulses by increasing electrical threshold and slowing action potential propagation, with epinephrine added as a vasoconstrictor to prolong anesthetic effect. Indicated for infiltration, nerve block, and epidural anesthesia in dental and surgical procedures.
LOE Approaching
Approaching loss of exclusivity with moderate competitive pressure (30/100) signals potential team restructuring and focus shift toward generic defense or pipeline transition initiatives.
Mechanism of Action
anesthetic. Local anesthetics block the generation and conduction of nerve impulses, presumably by increasing the threshold for electrical excitation in the nerve, by slowing the propagation of the nerve impulse, and by reducing the rate of rise of the action potential. In general, the progression…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
Working on Septocaine offers stable, operations-focused career experience in a mature, established injectable product with strong market presence. However, LOE approaching means this role is transitional—professionals should view it as a foundation for moving into generic strategy, portfolio optimization, or pipeline acceleration roles at Pfizer.
Brand Manager
Worked on SEPTOCAINE at Pfizer? Share your interview experience or compensation data (+7 days Pro)
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.