NDAINJECTIONINJECTABLE
Approved
Mar 2006
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
2/8 — Basic
SEPTOCAINE (articaine hydrochloride; epinephrine bitartrate) by Pfizer is anesthetic. First approved in 2006.
Drug data last refreshed 2d ago · AI intelligence enriched 3w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
SEPTOCAINE is a local anesthetic injectable combining articaine hydrochloride with epinephrine bitartrate, approved in 2006 for infiltration and nerve block anesthesia. It works by blocking nerve impulse generation and conduction while the epinephrine component acts as a vasoconstrictor to prolong local tissue concentration and duration of action. The product is used primarily in dental and minor surgical procedures requiring local anesthesia.
LOE Approaching
Product is in late-stage lifecycle with moderate competitive pressure (30/100), indicating potential resource reallocation and team restructuring ahead.
Mechanism of Action
anesthetic. Local anesthetics block the generation and conduction of nerve impulses, presumably by increasing the threshold for electrical excitation in the nerve, by slowing the propagation of the nerve impulse, and by reducing the rate of rise of the action potential. In general, the progression…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
Working on SEPTOCAINE offers limited long-term career growth as the product approaches loss of exclusivity with minimal clinical development activity. Roles are primarily commercial/sales-focused in a mature, price-competitive market segment with declining job openings.
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.