SEMPREX-D

LOE Approaching

acrivastine; pseudoephedrine hydrochloride

NDAORALCAPSULE
Approved
Mar 1994
Lifecycle
LOE Approaching
Competitive Pressure
30/100

Mechanism of Action

CLINICAL PHARMACOLOGY Acrivastine, a structural analog of triprolidine hydrochloride, exhibits H 1 -antihistaminic activity in isolated tissues, animals, and humans, and has sedative effects in humans (see ). The propionic acid derivative of acrivastine is a metabolite in several animal species (as…