SANDOSTATIN

LOE Approaching

octreotide acetate

NDAINJECTIONINJECTABLEPriority Review
Approved
Oct 1988
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
20

Mechanism of Action

hormone, somatostatin. It is an even more potent inhibitor of GH, glucagon, and insulin than somatostatin. Like somatostatin, it also suppresses luteinizing hormone (LH) response to gonadotropin releasing hormone (GnRH), decreases splanchnic blood flow, and inhibits release of serotonin, gastrin,…

Clinical Trials (5)

NCT01744249Phase 2/3Unknown

Sandostatin LAR and Axitinib vs Pbo in Pnts With Advanced Well-differentiated Non-pancreatic Neuroendocrine Carcinomas

Started Nov 2011
255 enrolled
Neuroendocrine TumorsAdvanced Cancer
NCT01121939Phase 2Completed

Combination of Bevacizumab, Pertuzumab, and Sandostatin for Adv. Neuroendocrine Cancers

Started May 2010
43 enrolled
Neuroendocrine Carcinoma
NCT00987168Phase 2Completed

Sandostatine® LP and Hyperinsulinism

Started May 2009
10 enrolled
Congenital Hyperinsulinism
NCT00510224Phase 2Terminated

Sandostatin for Patients With Androgen Independent Prostate Cancer

Started Jul 2007
13 enrolled
Prostate Cancer
NCT01424241Phase 4Completed

Effects of Sandostatin LAR® in Acromegaly

Started Oct 2006
21 enrolled
Acromegaly