RIMACTANE

LOE Approaching

rifampin

NDAORALCAPSULE
Approved
May 1971
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
20

Mechanism of Action

CLINICAL PHARMACOLOGY Oral Administration Rifampin is readily absorbed from the gastrointestinal tract. Peak serum concentrations in healthy adults and pediatric populations vary widely from individual to individual. Following a single 600 mg oral dose of rifampin in healthy adults, the peak serum…

Clinical Trials (5)

NCT07242781Phase 1Recruiting

A Study to Evaluate the Effect of Itraconazole and Rifampin on the Drug Levels of AR-LDD (BMS-986365) in Healthy Adult Male Participants

Started Dec 2025
42 enrolled
Healthy Volunteers
NCT06497465Phase 3Recruiting

Dolutegravir/Lamivudine Dual Therapy for ART-naïve People With HIV and TB Receiving Rifampin-based TB Treatment

Started Sep 2025
150 enrolled
TuberculosisHIV
NCT07018635Phase 1Completed

A Study to Assess the Effect of Itraconazole, Rifampin, and Acid-Reducing Agents on INCB161734 Pharmacokinetics When Administered Orally in Healthy Participants

Started Jul 2025
63 enrolled
Healthy Participants
NCT06909162Phase 1Recruiting

A Study to Evaluate the Effect of Food on the Single-Dose Pharmacokinetics and a Drug-Drug Interaction Evaluation of Itraconazole and Rifampin on INCB123667 When Administered Orally to Healthy Adult Participants

Started May 2025
51 enrolled
Healthy Participants
NCT06835465Phase 1Completed

A Study to Evaluate the Effect of Rifampin on the Pharmacokinetics of Divarasib in Healthy Participants

Started Feb 2025
18 enrolled
Healthy Participants