RIFADIN by Sanofi is mechanism of action rifampin inhibits dna-dependent rna polymerase activity in susceptible mycobacterium tuberculosis organisms. Approved for asymptomatic carriers of neisseria meningitidis to eliminate meningococci from the nasopharynx, meningococcal infection because of the possibility of the rapid emergence of resistant organisms, the treatment of all forms of tuberculosis. First approved in 1971.
Drug data last refreshed 2d ago
Mechanism of Action Rifampin inhibits DNA-dependent RNA polymerase activity in susceptible Mycobacterium tuberculosis organisms. Specifically, it interacts with bacterial RNA polymerase but does not inhibit the mammalian enzyme.
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