REXULTI

PeakSM

brexpiprazole

NDAORALTABLET
Approved
Jul 2015
Lifecycle
Peak
Competitive Pressure
0/100
Clinical Trials
20

Mechanism of Action

Pharmacologic Class:

Atypical Antipsychotic

Clinical Trials (5)

NCT06875986N/ARecruiting

REXULTI Drug General Use-results Survey (Excessive Motor Activity or Physically/Verbally Aggressive Behavior Due to Rapid Changes in Mood, Irritability, and/or Outbursts Associated With Dementia Due to Alzheimer's Disease)

Started Apr 2025
200 enrolled
Alzheimer Disease
NCT06036108Phase 1Completed

Food Effect Study of Brexpiprazole Once-weekly (QW) Formulation in Patients With Schizophrenia

Started Oct 2023
59 enrolled
Schizophrenia
NCT05962216N/ARecruiting

Real-life Assessment of Brexpiprazole (Rexulti) in Schizophrenia and in Depressive Disorders

Started Jul 2023
40 enrolled
PsychosisDepression
NCT05189977Phase 1Terminated

A Trial to Assess the Effects of Prazosin or Propranolol on Blood Pressure in the Presence of Brexpiprazole/Sertraline

Started Sep 2022
34 enrolled
Post-traumatic Stress Disorder (PTSD)
NCT05504486Phase 4Withdrawn

Open-label Brexpiprazole fMRI Trial in Adults With Major Depressive Disorder and Anxiety

Started Aug 2022
0
Major Depressive Disorder (MDD)

Loss of Exclusivity

LOE Date
Apr 12, 2033
86 months away
Patent Expiry
Apr 12, 2033
Exclusivity Expiry
May 9, 2028

Patent Records (5)

Patent #ExpiryTypeUse Code
9839637
Apr 12, 2026
Product
U-543
7888362
Apr 12, 2026
Substance
8349840
Apr 12, 2026
Product
U-1529
8618109
Apr 12, 2026
U-3281
8618109*PED
Oct 12, 2026