RETROVIR

LOE Approaching

zidovudine

NDAORALSOLUTIONPriority Review
Approved
Sep 1989
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
20

Mechanism of Action

Nucleoside Reverse Transcriptase Inhibitors

Pharmacologic Class:

Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor

Clinical Trials (5)

NCT00000789Phase 2Completed

A Randomized, Comparative Trial of Zidovudine (AZT) Versus 2',3'-Didehydro-3'-Deoxythymidine (Stavudine; d4T) in Children With HIV Infection

230 enrolled
HIV Infections
NCT00002307N/ACompleted

A Comparison of Zidovudine (AZT) and Stavudine in HIV-Infected Patients

HIV Infections
NCT00000978Phase 1Completed

A Study of Dideoxycytidine Plus Zidovudine in the Treatment of AIDS or Advanced AIDS Related Complex (ARC)

68 enrolled
HIV Infections
NCT00002265Phase 2Completed

An Open-Label, Multicenter Study to Evaluate the Safety and Tolerability of Dideoxycytidine (ddC) in Patients With AIDS or Advanced ARC Who Previously Demonstrated Intolerance to Zidovudine (AZT) in Protocol N3300 or N3492

HIV Infections
NCT00000961Phase 2Terminated

The Safety and Effectiveness of Hyperimmune Anti-HIV Intravenous Immunoglobulin (HVIG) Plus Zidovudine in HIV-Infected Infants

112 enrolled
HIV Infections