RETEVMO

Growth

selpercatinib

NDAORALCAPSULE
Approved
Apr 2024
Lifecycle
Growth
Competitive Pressure
0/100
Clinical Trials
21

Mechanism of Action

Rearranged during Transfection (RET) Inhibitors

Pharmacologic Class:

Kinase Inhibitor

Clinical Trials (5)

NCT06458036Phase 2Recruiting

Selpercatinib Pre-RAI in Patients With RET Fusion Thyroid Cancer (RAISE)

Started Jul 2024
13 enrolled
Differentiated Thyroid CancerPediatric CancerCancer+1 more
NCT05906836Phase 1Completed

A Drug Drug Interaction (DDI) Study of Selpercatinib (LY3527723) and Rosuvastatin in Healthy Participants

Started Jul 2023
28 enrolled
Healthy
NCT05668962Phase 2Recruiting

Restor. I-131 Upt. + Selpercatinib in RET F-P RAI-R TC

Started Mar 2023
30 enrolled
Thyroid CancerThyroid CarcinomaMetastatic Thyroid Cancer+3 more
NCT05324124Phase 1Completed

A Study of the Effect of Food on Selpercatinib (LY3527723) in Healthy Participants

Started Apr 2022
46 enrolled
Healthy
NCT04819100Phase 3Active Not Recruiting

A Study of Selpercatinib After Surgery or Radiation in Participants With Non-Small Cell Lung Cancer (NSCLC)

Started Dec 2021
152 enrolled
Carcinoma, Non-Small-Cell Lung

Loss of Exclusivity

LOE Date
Apr 10, 2039
159 months away
Patent Expiry
Apr 10, 2039
Exclusivity Expiry
Nov 29, 2031

Patent Records (5)

Patent #ExpiryTypeUse Code
10112942
Oct 10, 2037
SubstanceProduct
10137124
Oct 10, 2037
U-3951
10172851
Oct 10, 2037
U-3950
10137124*PED
Apr 10, 2038
10172851*PED
Apr 10, 2038