QUINIDINE GLUCONATE
LOE ApproachingNDAINJECTIONINJECTABLEPriority Review
Approved
Jul 1950
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
2/8 — Basic
Priority Review
QUINIDINE GLUCONATE by Eli Lilly and Company is mechanisms of action in patients with malaria, quinidine acts primarily as an intra-erythrocytic schizonticide, with little effect upon sporozites or upon pre-erythrocytic parasites. First approved in 1950.
Drug data last refreshed 14h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Quinidine gluconate is a Class Ia antiarrhythmic small molecule administered by injection for the treatment of cardiac arrhythmias including atrial flutter, atrial fibrillation, and paroxysmal supraventricular tachycardia. It works by depressing sodium current in cardiac tissue, slowing conduction and prolonging the effective refractory period to interrupt reentrant arrhythmias. Historically also used as an antimalarial agent against Plasmodium species.
LOE Approaching
Product approaching loss of exclusivity with minimal current linked job openings; career opportunities increasingly limited to niche cardiac and legacy portfolio roles.
Mechanism of Action
Mechanisms of action In patients with malaria, quinidine acts primarily as an intra-erythrocytic schizonticide, with little effect upon sporozites or upon pre-erythrocytic parasites. Quinidine is gametocidal to Plasmodium vivax and P. malariae , but not to P. falciparum. In cardiac muscle and in…
Indications
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.