QUINAPRIL HYDROCHLORIDE (quinapril hydrochloride) by PharmaIN is clinical pharmacology mechanism of action quinapril is deesterified to the principal metabolite, quinaprilat, which is an inhibitor of ace activity in human subjects and animals. Approved for hypertension, to lower blood pressure, the management of heart failure and 3 more indications. First approved in 2004.
Drug data last refreshed 21h ago
CLINICAL PHARMACOLOGY Mechanism of Action Quinapril is deesterified to the principal metabolite, quinaprilat, which is an inhibitor of ACE activity in human subjects and animals. ACE is a peptidyl dipeptidase that catalyzes the conversion of angiotensin I to the vasoconstrictor, angiotensin II. The…
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