NDAOPHTHALMICSOLUTION
Approved
Sep 2011
Lifecycle
Peak
Competitive Pressure
30/100
Clinical Trials
20
Data completeness
4/8 — Partial
PUR-WASH (water) by Otsuka is insulin, including insulin aspart products, is the regulation of glucose metabolism. Approved for glycemic control in adults. First approved in 2011.
Drug data last refreshed 5h ago · AI intelligence enriched 1mo ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
PUR-WASH is an ophthalmic solution containing water approved by FDA in 2011 for glycemic control in adults. The product's mechanism of action describes insulin regulation of glucose metabolism through peripheral glucose uptake stimulation and hepatic glucose production inhibition. This represents a significant data quality issue, as water has no pharmacological activity and the indication/MOA do not align with the ophthalmic route.
Peak
Product is in peak lifecycle stage with moderate competitive pressure (30), suggesting stable but challenged market position requiring defensive commercial strategy.
Mechanism of Action
insulin, including insulin aspart products, is the regulation of glucose metabolism. Insulin and its analogs lower blood glucose by stimulating peripheral glucose uptake, especially by skeletal muscle and fat, and by inhibiting hepatic glucose production. Insulin inhibits lipolysis and proteolysis,…
Indications (1)
Clinical Trials (20)
A Research Study Looking at the Effect of Timing of Meal After Dosing and Water Volume at Dosing on How the Medicine Zenagamtide is Taken up by the Body of Participants With Overweight or Obesity
Started Sep 2026
320 enrolled
OverweightObesity
WATER IV PCa (AS Sub-study)
Started Sep 2026
333 enrolled
Localized Prostate Cancer
Wastewater Surveillance for Carbapenem-Resistant Organism Outbreak Prediction in a Chinese Tertiary Hospital
Started Sep 2026
720 enrolled
Drug Resistance, BacterialCarbapenemsWastewater
Water Vapor Ablation for Grade Group 3 Prostate Cancer
Started Aug 2026
120 enrolled
Prostate Cancer
Water Vapor Ablation for Prostate Cancer: Long-Term Registry
Started Jun 2026
2,500 enrolled
Prostate Cancer
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.