NDAOPHTHALMICSOLUTION
Approved
Sep 2011
Lifecycle
Peak
Competitive Pressure
30/100
Clinical Trials
20
Data completeness
4/8 — Partial
PUR-WASH (water) by Otsuka is insulin, including insulin aspart products, is the regulation of glucose metabolism. Approved for glycemic control in adults. First approved in 2011.
Drug data last refreshed 20h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
PUR-WASH is an ophthalmic solution approved in 2011 for glycemic control in adults, despite a documented mechanism of action describing insulin's role in glucose metabolism. The product appears to be a water-based formulation with a misaligned indication-route combination that raises significant regulatory and clinical questions.
Peak
Product is in peak commercial stage with moderate competitive pressure (30), but lack of spending data suggests limited market traction or data integrity issues.
Mechanism of Action
insulin, including insulin aspart products, is the regulation of glucose metabolism. Insulin and its analogs lower blood glucose by stimulating peripheral glucose uptake, especially by skeletal muscle and fat, and by inhibiting hepatic glucose production. Insulin inhibits lipolysis and proteolysis,…
Indications (1)
Clinical Trials (20)
Water Vapor Ablation for Prostate Cancer: Long-Term Registry
Started Apr 2026
2,500 enrolled
Prostate Cancer
Effect of Watermelon on Cardiometabolic Health
Started Apr 2026
22 enrolled
Cardiometabolic Health IndicatorsWhole-body Antioxidant Capacity
Non-interventional Study to Evaluate the Anti-inflammatory Effects and the Clinical Efficacy of Topical Water Free Cyclosporin 0.1% Eye Drops in Patients With Dry Eye Disease and Associated Ocular Surface Inflammation Non-responding to Artificial Tears
Started Dec 2025
Computer-Aided Water Exchange Colonoscopy With and Without Linked-Color Imaging for Detection of Clinically Significant Serrated Lesions
Started Nov 2025
1,090 enrolled
Sessile Colonic PolypSerrated LesionSessile Serrated Lesion+1 more
Cold Water and Decision-Making
Started Aug 2025
40 enrolled
BehaviorStressQuality of Life+1 more
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.