PROZAC

LOE Approaching

fluoxetine hydrochloride

NDAORALCAPSULEPriority Review
Approved
Dec 1987
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
6

Mechanism of Action

unknown, it is presumed to be linked to its inhibition of CNS neuronal uptake of serotonin.

Clinical Trials (5)

NCT01247285Phase 1Completed

90 mg Fluoxetine Hydrochloride Capsules Under Non-Fasting Conditions

Started May 2001
26 enrolled
Healthy
NCT01247272Phase 1Completed

90 mg Fluoxetine Hydrochloride Capsules Under Fasting Conditions

Started May 2001
26 enrolled
Healthy
NCT00947076Phase 1Completed

To Demonstrate the Relative Bioavailability of Fluoxetine Hydrochloride Capsules, 40 mg

Started Feb 2001
30 enrolled
Depression
NCT00208897N/ACompleted

Does Fluoxetine Have an Effect on the CNS CRF Systems in Women Abused in Childhood?

Started Dec 1997
80 enrolled
Major Depressive Disorder
NCT00913718Phase 1Completed

To Demonstrate the Relative Bioavailability of Geneva and Dista (Prozac) 20 mg Fluoxetine Hydrochloride Capsules (Pulvules) In Healthy Adult Males Under Fasting Conditions

Started Jun 1996
46 enrolled
Depression