PROVOCHOLINE
LOE Approachingmethacholine chloride
NDAINHALATIONFOR SOLUTIONPriority Review
Approved
Oct 1986
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
3
Data completeness
2/8 — Basic
Priority Review
Drug data last refreshed 19h ago · AI intelligence enriched 1mo ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
PROVOCHOLINE (methacholine chloride) is a diagnostic agent administered via inhalation to assess airway hyperresponsiveness in patients suspected of having asthma or other obstructive airway diseases. It works as a bronchoconstrictor, causing temporary airway narrowing that helps clinicians identify abnormal airway reactivity. This is a diagnostic tool rather than a therapeutic agent.
LOE Approaching
As an older diagnostic agent approaching loss of exclusivity with moderate competitive pressure, this product likely operates with a lean, established commercial team focused on retention rather than expansion.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (3)
Bioequivalence Study of Methacholine Chloride
Started Jan 2024
20 enrolled
Healthy People
A Study to Evaluate Efficacy and Safety of Methacholine Chloride Challenge Test in Diagnosis of Adult Asthma
Started Apr 2014
Asthma
Study of Methacholine Chloride Inhalation Challenge in Children With Bronchial Asthma
Started Feb 2014
10 enrolled
Asthma
Career Relevance
Working on PROVOCHOLINE offers limited career growth given the product's mature stage, approaching loss of exclusivity, and minimal linked job openings (0 reported). This is a maintenance role best suited for professionals seeking stability in a niche diagnostic market rather than high-growth opportunity.
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.