PROVIGIL

LOE Approaching

modafinil

NDAORALTABLET
Approved
Dec 1998
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
20

Mechanism of Action

Pharmacologic Class:

Sympathomimetic-like Agent

Clinical Trials (5)

NCT06665230Phase 1Completed

A Clinical Study of MK-6552 and Modafinil in Healthy Men (MK-6552-005)

Started Sep 2023
12 enrolled
HealthyNarcolepsy
NCT03961997Phase 1Completed

Effect of Multiple Doses of Modafinil on the Pharmacokinetics of Single Dose Lorlatinib in Healthy Participants

Started Aug 2019
16 enrolled
AdultDrug InteractionsHealthy Volunteers+1 more
NCT02222441Phase 1Completed

Effect Of Modafinil And Pioglitazone On The Pharmacokinetics Of Palbociclib (PD-0332991)

Started Oct 2014
14 enrolled
Healthy
NCT02552303N/ACompleted

The Treatment of Insomnia Comorbid With Sleep Disordered Breathing Using Armodafinil and/or Cognitive Behavioral Therapy for Insomnia

Started Apr 2014
39 enrolled
Sleep ApneaInsomnia
NCT01781468Phase 3Completed

Armodafinil in Reducing Cancer-Related Fatigue in Patients With High Grade Glioma

Started Jun 2013
328 enrolled
Fatigue