PROMETHAZINE HYDROCHLORIDE AND CODEINE PHOSPHATE

Post-LOE

promethazine hydrochloride and codeine phosphate

ANDAORALSYRUP

Approved

Oct 2020

Lifecycle

Post-LOE

Competitive Pressure

30/100

Data completeness

3/8 — Basic

PROMETHAZINE HYDROCHLORIDE AND CODEINE PHOSPHATE (promethazine hydrochloride and codeine phosphate) is mu-opioid receptor, but with a much weaker affinity than morphine. Approved for adenoidectomy [see. First approved in 2020.

Drug data last refreshed 46m ago

Mechanism of Action

mu-opioid receptor, but with a much weaker affinity than morphine. The analgesic and antitussive properties of codeine have been speculated to come from its conversion to morphine. The precise mechanism of action of codeine and other opiates is not known; however, codeine is believed to act…

Indications (1)

adenoidectomy [see

Data Sources

Drug label: DailyMed / FDA
Clinical trials: ClinicalTrials.gov
Patent data: FDA Orange Book
Spending data: CMS Medicare

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.