NDAORALSUSPENSIONPriority Review
Approved
May 1976
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
4
Data completeness
4/8 — Partial
Priority Review
PROGLYCEM (diazoxide) by Teva is clinical pharmacology diazoxide produces a dose-related increase in blood glucose, due primarily to an inhibition of insulin release from the pancreas, and also to an extrapancreatic effect. First approved in 1976.
Drug data last refreshed 13h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
PROGLYCEM (diazoxide) is an oral small-molecule hyperglycemic agent approved in 1976 that raises blood glucose by inhibiting pancreatic insulin release and producing extrapancreatic metabolic effects. It is primarily used to manage hypoglycemia in patients with inoperable pancreatic tumors or those unable to tolerate other therapies. The drug's hyperglycemic effect begins within one hour and typically lasts up to eight hours with normal renal function.
LOE Approaching
Product is in late-stage lifecycle with moderate competitive pressure (30%), indicating a mature asset with potential consolidation or divestment activities ahead.
Mechanism of Action
CLINICAL PHARMACOLOGY Diazoxide produces a dose-related increase in blood glucose, due primarily to an inhibition of insulin release from the pancreas, and also to an extrapancreatic effect. The hyperglycemic effect of diazoxide begins within an hour and generally lasts no more than eight hours in…
Indications
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.