PROFENAL
LOE ApproachingNDAOPHTHALMICSOLUTION/DROPS
Approved
Dec 1988
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
2/8 — Basic
PROFENAL by Alcon is clinical pharmacology suprofen is one of a series of phenylalkanoic acids that have shown analgesic, antipyretic, and anti-inflammatory activity in animal inflammatory diseases. First approved in 1988.
Drug data last refreshed 10h ago · AI intelligence enriched 3w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
PROFENAL (suprofen) is a non-steroidal anti-inflammatory drug (NSAID) ophthalmic solution approved for intraocular use during cataract surgery. It works by inhibiting cyclooxygenase to reduce prostaglandin-mediated intraocular inflammation and prevent miosis (pupil constriction) during surgery. The drug is administered as topical eye drops to maintain pupil dilation and reduce post-operative inflammation.
LOE Approaching
As an older specialty ophthalmic product approaching loss of exclusivity, the brand team is likely in maintenance/rationalization mode with limited commercial expansion opportunities.
Mechanism of Action
CLINICAL PHARMACOLOGY Suprofen is one of a series of phenylalkanoic acids that have shown analgesic, antipyretic, and anti-inflammatory activity in animal inflammatory diseases. Its mechanism of action is believed to be through inhibition of the cyclooxygenase enzyme that is essential in the…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.