NDAORALTABLET, EXTENDED RELEASE
Approved
Jan 1996
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
3/8 — Basic
PROCANBID (procainamide hydrochloride) by Pfizer is clinical pharmacology procainamide (pa) increases the effective refractory period of the atria, and to a lesser extent the bundle of his-purkinje system and ventricles of the heart. Approved for documented ventricular arrhythmias, such, that and 1 more indications. First approved in 1996.
Drug data last refreshed 10h ago · AI intelligence enriched 3w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
PROCANBID is a procainamide hydrochloride extended-release tablet, a Class 1A antiarrhythmic agent used to treat documented ventricular arrhythmias. It works by increasing the effective refractory period of cardiac tissue, reducing impulse conduction velocity, and decreasing myocardial excitability through inhibition of ectopic pacemaker activity. The drug is structurally similar to quinidine but has weaker vagal blocking action and less cardiac depression.
LOE Approaching
PROCANBID is approaching loss of exclusivity as a legacy antiarrhythmic with likely limited team size and focus on managed decline strategies.
Mechanism of Action
CLINICAL PHARMACOLOGY Procainamide (PA) increases the effective refractory period of the atria, and to a lesser extent the bundle of His-Purkinje system and ventricles of the heart. It reduces impulse conduction velocity in the atria, His-Purkinje fibers, and ventricular muscle, but has variable…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.