NDAINHALATIONPOWDER, METERED
Approved
Mar 2015
Lifecycle
Peak
Competitive Pressure
30/100
Clinical Trials
12
Data completeness
5/8 — Partial
PROAIR RESPICLICK (albuterol sulfate) by Teva is clinical pharmacology the prime action of beta-adrenergic drugs is to stimulate adenyl cyclase, the enzyme which catalyzes the formation of cyclic-3',5'-adenosine monophosphate (cyclic amp) from adenosine triphosphate (atp). Approved for asthma. First approved in 2015.
Drug data last refreshed 20h ago · AI intelligence enriched 3w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
PROAIR RESPICLICK is an albuterol sulfate inhaled powder approved in 2015 by Teva for the treatment and prevention of exercise-induced bronchospasm in patients 4 years of age and older. It is a short-acting beta-2 adrenergic agonist (SABA) that works by stimulating adenyl cyclase to increase cyclic AMP levels, which relaxes bronchial smooth muscle and improves airflow. The drug demonstrates preferential beta-2 receptor selectivity with faster onset (improvement within 5 minutes) and longer duration compared to older agonists like isoproterenol, while producing fewer cardiovascular side effects. It is positioned as a rescue/quick-relief therapy in asthma and exercise-induced bronchospasm management.
$0.0BPart D
Mechanism of Action
CLINICAL PHARMACOLOGY The prime action of beta-adrenergic drugs is to stimulate adenyl cyclase, the enzyme which catalyzes the formation of cyclic-3',5'-adenosine monophosphate (cyclic AMP) from adenosine triphosphate (ATP). The cyclic AMP thus formed mediates the cellular responses. In vitro…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.