NDAINTRAMUSCULARPOWDER
Approved
Dec 1990
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
1/8 — Limited
Drug data last refreshed 2d ago · AI intelligence enriched 3w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
PRIMAXIN is a fixed-dose combination of imipenem (a broad-spectrum beta-lactam antibiotic) and cilastatin (a renal dehydropeptidase inhibitor) administered intramuscularly as a powder for reconstitution. It is indicated for serious infections caused by susceptible gram-positive, gram-negative, and anaerobic bacteria. Cilastatin prevents renal metabolism of imipenem, allowing higher urinary concentrations and reducing nephrotoxicity.
LOE Approaching
As a product approaching loss of exclusivity with moderate competitive pressure (30/100), brand teams face shrinking market share and cost-containment measures; roles emphasize managed care and defensive positioning rather than growth initiatives.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
Working on PRIMAXIN offers limited career growth given its LOE-approaching status and minimal linked job postings (0 open roles). Roles emphasize defensive market strategy, payer negotiations, and institutional relationships rather than innovation or expansion.
Brand ManagerAccount Manager
Worked on PRIMAXIN at Merck & Co.? Share your interview experience or compensation data (+7 days Pro)
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.