PRIFTIN

LOE Approaching

rifapentine

NDAORALTABLETPriority Review
Approved
Jun 1998
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
9

Mechanism of Action

Rifapentine, a cyclopentyl rifamycin, is an antimycobacterial agent [see ] .

Pharmacologic Class:

Rifamycin Antimycobacterial

Clinical Trials (5)

NCT05630872Phase 2Completed

Pharmacokinetics and Safety of Double-dose Dolutegravir When Used With Rifapentine for HIV-associated Tuberculosis

Started Feb 2024
30 enrolled
HIV-associated Tuberculosis
NCT04551573Phase 4Withdrawn

A Study of the Pharmacokinetic and Pharmacodynamic Interactions Between Bictegravir, Tenofovir Alafenamide and Rifapentine in Healthy Adult Subjects

Started May 2021
0
TuberculosisHiv
NCT04272242Phase 2Terminated

Drug-Drug Interactions Between Rifapentine and Dolutegravir in HIV/LTBI Co-Infected Individuals

Started Feb 2021
37 enrolled
HIV InfectionLTBI
NCT03886701Phase 1Completed

Doravirine, Rifapentine and Isoniazid Interaction

Started Apr 2019
11 enrolled
Latent TuberculosisHuman Immunodeficiency VirusRifamycins Causing Adverse Effects in Therapeutic Use+1 more
NCT01690403Phase 1Completed

Interaction Study to Assess the Pharmacokinetic Interaction of Oral Administration of Rifapentine on ATRIPLA™ in HIV Patients

Started Dec 2012
25 enrolled
Tuberculosis