PRED MILD

LOE Approaching

prednisolone acetate

NDAOPHTHALMICSUSPENSION/DROPS
Approved
Nov 1972
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
6

Mechanism of Action

CLINICAL PHARMACOLOGY Prednisolone acetate is a glucocorticoid that, on the basis of weight, has 3 to 5 times the anti-inflammatory potency of hydrocortisone. Glucocorticoids inhibit the edema, fibrin deposition, capillary dilation, and phagocytic migration of the acute inflammatory response, as…

Clinical Trials (5)

NCT01384266N/ACompleted

A Comparison of 0.5% Loteprednol Etabonate Versus 1% Prednisolone Acetate Following Cataract Surgery

Started May 2010
90 enrolled
Intraocular Inflammation
NCT01244334Phase 4Completed

Study of Difluprednate vs. Prednisolone Acetate on Visual Acuity, and Corneal Edema Following Cataract Surgery.

Started Mar 2009
52 enrolled
CataractsCorneal EdemaRetinal Structural Change, Deposit and Degeneration+1 more
NCT00198523Phase 3Completed

A Bioequivalence Study of Tobramycin and Prednisolone Acetate Compared to PredForte

Started Jul 2005
132 enrolled
Eye InfectionsPostoperative Complications
NCT00139295Phase 3Completed

Comparison of Hylastan to Methylprednisolone Acetate in Patients With Symptomatic Osteoarthritis of the Knee

Started Oct 2004
Osteoarthritis, Knee
NCT00170729Phase 4Completed

A Study to Compare Ocular Safety and Tolerability of Eye Drops Containing Prednisolone Acetate in Patients With Intraocular Inflammation After Cataract Surgery

Started Aug 2004
62 enrolled
Cataract Surgery