NDAOPHTHALMICSUSPENSION/DROPS
Approved
May 1973
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
9
Data completeness
4/8 — Partial
PRED FORTE (prednisolone acetate) by AbbVie is clinical pharmacology prednisolone acetate is a glucocorticoid that, on the basis of weight, has 3 to 5 times the anti-inflammatory potency of hydrocortisone. First approved in 1973.
Drug data last refreshed Yesterday
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
PRED FORTE (prednisolone acetate) is a potent topical ophthalmic glucocorticoid suspension approved in 1973 that treats inflammatory and allergic eye conditions including uveitis, conjunctivitis, corneal edema, and diabetic macular edema. It works by inhibiting the acute inflammatory cascade, reducing edema, fibrin deposition, capillary dilation, and phagocytic migration. With 3–5 times the anti-inflammatory potency of hydrocortisone, it is a standard-of-care agent for short-term ocular inflammation management.
$1MPart D
LOE ApproachingDeclining
Mature, low-volume product with limited growth runway and small commercial team aligned to legacy ophthalmic franchise.
Mechanism of Action
CLINICAL PHARMACOLOGY Prednisolone acetate is a glucocorticoid that, on the basis of weight, has 3 to 5 times the anti-inflammatory potency of hydrocortisone. Glucocorticoids inhibit the edema, fibrin deposition, capillary dilation, and phagocytic migration of the acute inflammatory response, as…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (9)
A Comparison of 0.5% Loteprednol Etabonate Versus 1% Prednisolone Acetate Following Cataract Surgery
Started May 2010
90 enrolled
Intraocular Inflammation
Study of Difluprednate vs. Prednisolone Acetate on Visual Acuity, and Corneal Edema Following Cataract Surgery.
Started Mar 2009
52 enrolled
CataractsCorneal EdemaRetinal Structural Change, Deposit and Degeneration+1 more
Study of T-PRED(TM) Compared to Pred Forte(R) II
Started Feb 2009
172 enrolled
Cataract
Study of T-PRED(TM) Compared to Pred Forte(R)
Started May 2008
64 enrolled
Cataract
Comparing Acular LS and Pred Forte in Reducing Post-selective Laser Trabeculoplasty Anterior Chamber Flare and Cells
Started May 2007
31 enrolled
Open Angle Glaucoma
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.