NDATOPICALSPONGE
Approved
Oct 1978
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
20
Data completeness
2/8 — Basic
Drug data last refreshed Yesterday
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
PRE-OP is a topical hexachlorophene-based surgical sponge approved in 1978 for preoperative skin antisepsis and staphylococcal infection prevention. Hexachlorophene is a halogenated phenolic compound that acts as a broad-spectrum antimicrobial agent for topical use. The sponge formulation enables direct application in surgical settings to reduce bacterial contamination.
LOE Approaching
Legacy product approaching loss of exclusivity with limited commercial investment; small team managing mature brand with defensive positioning.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (20)
SATURN-STS: Phase II Study of Neoadjuvant Atezolizumab With Doxorubicin, Concurrent Atezolizumab With Pre-operative Radiation Therapy and Adjuvant Atezolizumab in Patients With High-risk Surgically Resectable Extremity and Truncal Soft Tissue Sarcoma
Started Sep 2025
50 enrolled
Soft Tissue Sarcoma
Pre-operative Vabysmo in Patients With Non-clearing Vitreous Hemorrhage Secondary to Proliferative Diabetic Retinopathy
Started Jul 2024
100 enrolled
Diabetic RetinopathyVitreous Hemorrhage Due to Diabetes Mellitus
Stage II-IIIa Urothelial Cancer Randomizing Pre-operative Nivolumab With or Without Relatlimab
Started Feb 2024
90 enrolled
Urologic NeoplasmsUrogenital NeoplasmsNeoplasms by Site+8 more
Pre-operative Atezolizumab in Patients With Resectable, Human Papillomavirus Related Oropharyngeal Carcinoma
Started Oct 2023
20 enrolled
Oropharynx Cancer, Stage I
Pre-Operative Ketamine Infusion for Post Operative Pain Control After Revision Spinal Surgery
Started Sep 2023
40 enrolled
Revision Spine SurgeryFusion of SpineCervical Fusion+1 more
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.