Mechanism of Action
competitive, direct thrombin inhibitors. Because thrombin (serine protease) enables the conversion of fibrinogen into fibrin during the coagulation cascade, its inhibition prevents the development of a thrombus. Both free and clot-bound thrombin, and thrombin-induced platelet aggregation are…
Indications (8)
Clinical Trials (5)
A Study in the United Sates That Looks at the Safety and Effectiveness of Pradaxa Pellets in Children Aged 3 Months to Less Than 12 Years Who Need Treatment of a Blood Clot or Who Have Had a Blood Clot and Are at Risk of Developing Another Blood Clot
Clinical Trial to Assess the Safety and Pharmacokinetics of RDG-17012 Capsule and Pradaxa® Capsule in Healthy Male Volunteers
Japanese Pradaxa PMS, Long Term
Pradaxa Tablet Proton Pump Inhibitor (PPI) Bioavailability (BA) Study in Japan
A Pharmacokinetic Interaction Study Between Odalasvir, Given as a Single Agent or in Combination With Simeprevir, and Dabigatran Etexilate Mesylate in Healthy Participants
Loss of Exclusivity
Patent Records (4)
| Patent # | Expiry | Type | Use Code |
|---|---|---|---|
| 7932273 | Sep 7, 2025Expired | SubstanceProduct | — |
| 7932273*PED | Mar 7, 2026 | — | |
| 9034822 | Jan 20, 2031 | U-1759 | |
| 9034822*PED | Jul 20, 2031 | — |