NDAINJECTIONINJECTABLE
Lifecycle
Pre-Launch
Data completeness
1/8 — Limited
POLYCILLIN-N (ampicillin sodium) by Bristol Myers Squibb is clinical pharmacology general immediately after completion of a 15-minute intravenous infusion of ampicillin and sulbactam, peak serum concentrations of ampicillin and sulbactam are attained.
Drug data last refreshed 18h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
POLYCILLIN-N is an injectable combination of ampicillin sodium and sulbactam sodium, a beta-lactam antibiotic with beta-lactamase inhibitor used to treat bacterial infections. It works by inhibiting bacterial cell wall synthesis while sulbactam protects ampicillin from enzymatic degradation by beta-lactamase-producing organisms. The combination achieves rapid peak serum concentrations with approximately 1-hour half-life and broad tissue penetration including meninges.
Pre-Launch
As a pre-launch injectable antibiotic, this product will require field-based infectious disease and hospital formulary teams; commercial scale will be determined by formulary adoption and hospital acquisition contracts.
Mechanism of Action
CLINICAL PHARMACOLOGY General Immediately after completion of a 15-minute intravenous infusion of ampicillin and sulbactam, peak serum concentrations of ampicillin and sulbactam are attained. Ampicillin serum levels are similar to those produced by the administration of equivalent amounts of…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.