NDATOPICALCREAM
Approved
Jun 2006
Lifecycle
Peak
Competitive Pressure
8/100
Clinical Trials
2
Data completeness
4/8 — Partial
PLIAGLIS (lidocaine and tetracaine) by Crescita Therapeutics is amide-type local anesthetic agent and tetracaine is an ester-type local anesthetic agent. First approved in 2006.
Drug data last refreshed 14h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
PLIAGLIS is a topical cream combining lidocaine (amide-type) and tetracaine (ester-type) local anesthetics that block sodium ion channels to provide dermal analgesia. Applied to intact skin, it releases both agents to achieve localized pain relief. The product is indicated for topical dermatological anesthesia in procedural settings.
Peak4.2 years to LOE
Product is in peak commercial phase with high competitive pressure (8/10), suggesting a mature, competitive market with established field and brand infrastructure.
Mechanism of Action
amide-type local anesthetic agent and tetracaine is an ester-type local anesthetic agent. Both lidocaine and tetracaine block sodium ion channels required for the initiation and conduction of neuronal impulses which, in certain instances, results in local anesthesia. When applied to intact skin,…
Pharmacologic Class:
Amide Local Anesthetic
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (2)
A Non-interventional Study to Evaluate the Use of Pliaglis in Daily Practice
Started Feb 2013
582 enrolled
Health Knowledge, Attitudes, Practice
Evaluate Efficacy, Safety & Subject Satisfaction of Pain Management With Pliaglis® Cream for Dermal Filler Injections
Started Jul 2008
51 enrolled
Nasolabial Folds
Why This Matters for Your Career
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.