PLEGISOL IN PLASTIC CONTAINER
LOE Approachingpotassium chloride, sodium chloride, calcium chloride, and magnesium chloride
NDAPERFUSION, CARDIACSOLUTIONPriority Review
Approved
Feb 1982
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Mechanism of Action
CLINICAL PHARMACOLOGY Plegisol with added sodium bicarbonate when cooled and instilled into the coronary artery vasculature, causes prompt arrest of cardiac electromechanical activity, combats intracellular ion losses and buffers ischemic acidosis. When used with hypothermia and ischemia, the…