PLAQUENIL
LOE Approachinghydroxychloroquine sulfate
NDAORALTABLET
Approved
Apr 1955
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
2
Mechanism of Action
4-aminoquinoline antimalarial [see ] and antirheumatic agent. Rheumatoid Arthritis, Systemic Lupus Erythematosus and Chronic Discoid Lupus Erythematosus The mechanisms underlying the anti-inflammatory and immunomodulatory effects of PLAQUENIL in the treatment of rheumatoid arthritis, chronic…
Indications (18)
acutechronic rheumatoid arthritis in adultssystemic lupus erythematosus in adultschronic discoid lupus erythematosus in adultsuncomplicated malaria due to Plasmodium falciparumPlasmodium malariaePlasmodium ovalePlasmodium vivax in adultrheumatoid arthritis in adultscomplicated malariachloroquinehydroxychloroquine-resistant strains of Plasmodium speciesmalaria acquired in geographic areas where chloroquine resistance occursthe Plasmodium species has not been identifiedrelapses of PPlasmodium vivaxmalaria by chloroquinerheumatoid arthritis
Clinical Trials (2)
Multicenter Study Assessing the Efficacy & Safety of Hydroxychloroquine Sulfate in Patients With Systemic Lupus Erythematosus or Cutaneous Lupus Erythematosus With Active Lupus Erythematosus Specific Skin Lesion
Started Mar 2012
103 enrolled
Cutaneous Lupus Erythematosus-Systemic Lupus Erythematosus
To Demonstrate the Relative Bioavailability of Hydroxychloroquine Sulfate, 200 mg Tablets
Started Jul 1993
72 enrolled
ImmunosuppressionRheumatism