NDAINJECTIONINJECTABLE
Approved
Nov 1980
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
20
Data completeness
4/8 — Partial
PITOCIN (oxytocin) by Pfizer is clinical pharmacology uterine motility depends on the formation of the contractile protein actomyosin under the influence of the ca-dependent phosphorylating enzyme myosin light-chain kinase. First approved in 1980.
Drug data last refreshed 8h ago · AI intelligence enriched 4d ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
PITOCIN (oxytocin) is a synthetic oxytocic agent that promotes uterine contractions by increasing intracellular calcium in myometrial smooth muscle. It is used to induce or augment labor and to control postpartum hemorrhage. The drug works by binding to oxytocin receptors on the uterine myometrium, whose concentration increases dramatically during pregnancy and peaks at term.
LOE Approaching
Approaching loss of exclusivity creates urgency in commercial teams to defend market share and optimize supply chain efficiency.
Mechanism of Action
CLINICAL PHARMACOLOGY Uterine motility depends on the formation of the contractile protein actomyosin under the influence of the Ca-dependent phosphorylating enzyme myosin light-chain kinase. Oxytocin promotes contractions by increasing the intracellular Ca. Oxytocin has specific receptors in the…
Pharmacologic Class:
Oxytocic
Indications
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.