PITOCIN

LOE Approaching

oxytocin

NDAINJECTIONINJECTABLE
Approved
Nov 1980
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
20

Mechanism of Action

CLINICAL PHARMACOLOGY Uterine motility depends on the formation of the contractile protein actomyosin under the influence of the Ca-dependent phosphorylating enzyme myosin light-chain kinase. Oxytocin promotes contractions by increasing the intracellular Ca. Oxytocin has specific receptors in the…

Pharmacologic Class:

Oxytocic

Clinical Trials (5)

NCT04789148Phase 1Recruiting

Effects of Intranasal Oxytocin in Patients With Arginine-vasopressin Deficiency

Started Sep 2025
40 enrolled
Vasopressin Deficiency
NCT06692621N/ACompleted

Effects of Carbetocin and Oxytocin Used in Cesarean Sections on Postoperative Pain

Started Oct 2024
NCT05754073Phase 2Recruiting

Oxytocin Effects on Bone in Children With Autism Spectrum Disorder

Started Aug 2023
96 enrolled
Autism Spectrum DisorderBone Health
NCT04732247Phase 2Completed

Oxytocin for Oxidative Stress and Inflammation

Started Feb 2022
40 enrolled
Oxidative StressInflammation
NCT05093296Phase 2/3Completed

Oxytocin and Naltrexone: Investigation of Combined Effects on Stress- and Alcohol Cue-induced Craving in Alcohol Use Disorder

Started Dec 2021
62 enrolled
Alcohol Use DisorderAlcoholismAlcohol Addiction