NDAVAGINALGEL
Approved
May 2020
Lifecycle
Peak
Competitive Pressure
0/100
Clinical Trials
1
Data completeness
6/8 — Strong
PHEXXI (lactic acid, l-, citric acid monohydrate, and potassium bitartrate) by Evofem Biosciences is studies, phexxi produced a normal vaginal ph range (ph 3. Approved for pregnancy in females of reproductive potential for use. First approved in 2020.
Drug data last refreshed 20h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
PHEXXI is a non-hormonal vaginal gel combining lactic acid, citric acid monohydrate, and potassium bitartrate for contraception. It works by maintaining vaginal pH in the acidic range (3.5–4.5) in the presence of semen, reducing sperm motility and preventing pregnancy. It is indicated for females of reproductive potential seeking non-hormonal birth control.
$0.086BPart D
Peak6.9 years to LOEProduct is in peak commercial lifecycle with minimal Part D penetration, suggesting significant untapped market opportunity and sustained commercial team investment.
Mechanism of Action
studies, Phexxi produced a normal vaginal pH range (pH 3.5 – 4.5) in the presence of semen. In clinical studies, post-coital testing demonstrated pH < 5 in the majority of subjects, and sperm motility reduction.
Indications (1)
Clinical Trials (1)
Study of Contraceptive Efficacy & Safety of Phexxi™ (Previously Known as Amphora) Gel Compared to Conceptrol Vaginal Gel
Started Apr 2011
3,389 enrolled
Contraception
Career Relevance
Working on PHEXXI positions you in a high-growth, category-defining non-hormonal contraceptive with limited competition and substantial market runway until 2033. Current hiring focuses on specialty sales in major metropolitan markets, indicating aggressive commercial expansion and market share capture strategies.
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.