NDAVAGINALGEL
Approved
May 2020
Lifecycle
Peak
Competitive Pressure
0/100
Clinical Trials
1
Data completeness
6/8 — Strong
PHEXXI (lactic acid, l-, citric acid monohydrate, and potassium bitartrate) by Evofem Biosciences is studies, phexxi produced a normal vaginal ph range (ph 3. Approved for pregnancy in females of reproductive potential for use. First approved in 2020.
Drug data last refreshed 14h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
PHEXXI is a non-hormonal vaginal contraceptive gel containing lactic acid, citric acid monohydrate, and potassium bitartrate that prevents pregnancy by maintaining vaginal pH in the acidic range (3.5–4.5) to reduce sperm motility. Applied vaginally before intercourse, it works by creating an inhospitable environment for sperm in the presence of semen. Clinical studies demonstrated pH maintenance below 5 post-coitally with demonstrated sperm motility reduction.
$0.086MPart D
Peak6.6 years to LOEProduct is in peak lifecycle stage but shows minimal commercial traction with only 200 Part D claims in 2023, suggesting limited market penetration and potential team constraints.
Mechanism of Action
studies, Phexxi produced a normal vaginal pH range (pH 3.5 – 4.5) in the presence of semen. In clinical studies, post-coital testing demonstrated pH < 5 in the majority of subjects, and sperm motility reduction.
Indications (1)
Clinical Trials (1)
Study of Contraceptive Efficacy & Safety of Phexxi™ (Previously Known as Amphora) Gel Compared to Conceptrol Vaginal Gel
Started Apr 2011
3,389 enrolled
Contraception
Career Relevance
PHEXXI offers a niche career opportunity in women's health and non-hormonal contraception, though the minimal linked job openings (0) reflect the product's limited commercial scale. Working on this product provides deep expertise in an underserved market segment but may offer fewer advancement opportunities compared to larger franchise brands.
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.