PHENYLEPHRINE HYDROCHLORIDE

Peak

phenylephrine hydrochloride

NDAOPHTHALMICSOLUTION/DROPS
Approved
Jan 2015
Lifecycle
Peak
Competitive Pressure
30/100
Clinical Trials
4

Mechanism of Action

α-1 adrenergic agonist drug that is used in ophthalmology mainly for its mydriatic effect. After topical application to the conjunctiva, phenylephrine acts directly on α-adrenergic receptors in the eye, producing contraction of the dilator muscle of the pupil and constriction of the arterioles in…

Clinical Trials (4)

NCT01448057Phase 3Completed

Evaluation of Efficacy and Safety of Tablets of Paracetamol, Dimethindene Maleate and Phenylephrine Hydrochloride in Reducing Symptoms of Common Cold and Flu

Started Jul 2013
341 enrolled
Upper Respiratory Tract InfectionNasal CongestionRhinorrhea+1 more
NCT04534452Phase 3Completed

Study to Find Out Whether Participants With a History of Stuffy Nose Due to Allergic Reactions in the Nose Would Intend to Buy Drug Phenylephrine Hydrochloride Extended Release Tablets After Receiving it Once in This Study

Started May 2012
347 enrolled
Nasal Congestion Due to Allergic Rhinitis
NCT01026961Phase 1/2Withdrawn

Safety of Phenylephrine Hydrochloride, Acetaminophen, Dimethindene Maleate Compared to Phenylephrine Hydrochloride Alone in Healthy Volunteers

Started Sep 2010
0
Heart RateBlood PressureArrhythmias
NCT00976209Phase 3Completed

Consumer Preference Study of Two Formulations of Phenylephrine Hydrochloride (Study CL2008-15)(P07530)(COMPLETED)

Started Aug 2009
331 enrolled
Vasomotor RhinitisSeasonal Allergic Rhinitis