NDAORALSYRUP
Approved
Jan 1952
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
1/8 — Limited
Drug data last refreshed 2d ago · AI intelligence enriched 3w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Phenergan with Codeine is an oral syrup combination of codeine phosphate (opioid analgesic) and promethazine hydrochloride (antihistamine/antiemetic) used to treat cough and upper respiratory symptoms. The codeine suppresses cough reflex while promethazine provides antihistamine effects and potentiates analgesia. This is a legacy small-molecule product approved in 1952.
LOE Approaching
As a product approaching loss of exclusivity with moderate competitive pressure (30%), brand teams face defensive positioning and cost-containment focus rather than growth initiatives.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
Working on Phenergan with Codeine offers limited growth trajectory but provides solid experience in heritage product management, generic transition, and opioid regulation compliance. This is primarily a defensive, cost-management role suited to mid-career professionals managing portfolio decline rather than launching innovation.
Brand ManagerProduct Manager
Worked on PHENERGAN W/ CODEINE at ANI Pharmaceuticals? Share your interview experience or compensation data (+7 days Pro)
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.