NDAORALCAPSULE, EXTENDED RELEASE
Approved
Apr 1979
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
3/8 — Basic
PHENDIMETRAZINE TARTRATE (phendimetrazine tartrate) by Novartis is clinical pharmacology phendimetrazine tartrate is a phenylalkylamine sympathomimetic amine with pharmacological activity similar to the prototype drugs of this class used in obesity, the amphetamines. Approved for the management of exogenous obesity, equal to 30 kg/m, greater than and 2 more indications. First approved in 1979.
Drug data last refreshed 17h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Phendimetrazine tartrate is a sympathomimetic amine anorectic (appetite suppressant) approved for management of exogenous obesity in patients with BMI ≥30 kg/m² or ≥27 kg/m² with comorbidities. It works by stimulating the central nervous system and elevating blood pressure to reduce appetite, with the extended-release formulation approximating three immediate-release doses.
LOE Approaching
Approaching loss of exclusivity signals declining revenue and smaller team focus; commercial roles likely transitioning to cost management and market defense strategies.
Mechanism of Action
CLINICAL PHARMACOLOGY Phendimetrazine tartrate is a phenylalkylamine sympathomimetic amine with pharmacological activity similar to the prototype drugs of this class used in obesity, the amphetamines. Actions include central nervous system stimulation and elevation of blood pressure. Tachyphylaxis…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.