NDAORALTABLET
Approved
Aug 1999
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
20
Data completeness
3/8 — Basic
PEPCID AC (famotidine) by Johnson & Johnson is histamine h2 receptor antagonists [moa]. First approved in 1999.
Drug data last refreshed 10h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
PEPCID AC (famotidine) is an oral H2 receptor antagonist approved for treating heartburn, acid indigestion, and gastroesophageal reflux disease (GERD). It works by reducing stomach acid production through selective histamine H2 receptor blockade. This over-the-counter medication is widely used for symptomatic relief in both acute and chronic acid-related conditions.
LOE Approaching
LOE-approaching lifecycle with moderate competitive pressure (30) suggests teams are rightsizing or transitioning to adjacent opportunities rather than expanding.
Mechanism of Action
Histamine H2 Receptor Antagonists
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (20)
Study on the Effect of Famotidine on Pharmacokinetics of Taletrectinib
Started Aug 2026
56 enrolled
Healthy Adult Participants
Evaluate the Effects of Famotidine or Rabeprazole on the PK of Nirogacestat
Started Aug 2025
24 enrolled
Healthy
A Study to Assess the Effect of Famotidine on the Drug Levels of Afimetoran in Healthy Participants
Started Jul 2023
32 enrolled
Healthy Volunteers
A Study to Determine the Effect of Famotidine on the Drug Levels of BMS-986256 in Healthy Participants
Started Jun 2021
22 enrolled
Healthy Participants
Study to Assess the Effect of Acid-reducing Agent Famotidine on the Drug Levels of BMS-986256 in Healthy Participants
Started Jul 2020
35 enrolled
Healthy Participants
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.