PENTETATE ZINC TRISODIUM

LOE Approaching

pentetate zinc trisodium

NDAINHALATION, INTRAVENOUSSOLUTIONPriority Review
Approved
Aug 2004
Lifecycle
LOE Approaching
Competitive Pressure
30/100

Mechanism of Action

Zn-DTPA forms stable chelates with metal ions by exchanging zinc for a metal of greater binding capacity. The radioactive chelates are then excreted by glomerular filtration into the urine. In animal studies, Zn-DTPA forms less stable chelates with uranium and neptunium in vivo resulting in…

Indications (4)

individuals with knownsuspected internal contamination with plutoniumamericiumcurium to increase the rates of elimination
External Resources
DailyMed
Full prescribing information
FDA Drugs@FDA
FDA approval history
RxNorm
Drug nomenclature & identifiers