NDAINJECTIONINJECTABLE
Lifecycle
Pre-Launch
Clinical Trials
20
Data completeness
2/8 — Basic
PEMETREXED FOR INJECTION (pemetrexed) by Dr. Reddy's Laboratories is folic acid metabolism inhibitors [moa].
Drug data last refreshed 9h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Pemetrexed for injection is a folic acid metabolism inhibitor administered intravenously, designed to treat cancer by disrupting DNA synthesis in rapidly dividing cells. This small-molecule chemotherapy agent is indicated for various solid tumors where antifolate therapy provides clinical benefit. The drug works by inhibiting multiple enzymes in the folate pathway, leading to cell cycle arrest and apoptosis.
Pre-Launch
This is a pre-launch product, signaling early-stage commercial infrastructure development and potential for substantial team expansion upon market entry.
Mechanism of Action
Folic Acid Metabolism Inhibitors
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (20)
Zipalertinib With Carboplatin and Pemetrexed for the Treatment of Resectable, Stage II-IIIB, Non-Small Cell Lung Cancer
Started Jun 2027
16 enrolled
Lung Non-Squamous Non-Small Cell Carcinoma
Golcadomide With Pemetrexed, Rituximab, and Dexamethasone for Relapsed and Refractory CNS Lymphomas
Started Jun 2026
18 enrolled
Large B-cell LymphomaCentral Nervous System Lymphoma
Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)
Started Nov 2025
500 enrolled
Non-Small Cell Lung Cancer
A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer
Started Oct 2025
600 enrolled
Non-Small Cell Lung CancerKRAS G12C Lung Cancer
Intrathecal Injection Pemetrexed And Bevacizumab in Patients With Leptomeningeal Metastases in NSCLC
Started Dec 2024
19 enrolled
Lung Cancer (NSCLC)Leptomeningeal Metastasis
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.