NDAINJECTIONINJECTABLE
Lifecycle
Pre-Launch
Clinical Trials
20
Data completeness
2/8 — Basic
PEMETREXED FOR INJECTION (pemetrexed) by Dr. Reddy's Laboratories is folic acid metabolism inhibitors [moa].
Drug data last refreshed 22h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Pemetrexed is a folic acid metabolism inhibitor administered by injection for the treatment of certain cancers, including non-small cell lung cancer and mesothelioma. It works by disrupting folate-dependent enzymes critical to cell replication and DNA synthesis. This mechanism makes it effective as both a single agent and combination therapy in oncology.
PRE_LAUNCH
Pre-launch stage indicates active infrastructure building; commercial team expansion likely during ramp-up phase with focus on market entry strategy and provider education.
Mechanism of Action
Folic Acid Metabolism Inhibitors
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (20)
Zipalertinib With Carboplatin and Pemetrexed for the Treatment of Resectable, Stage II-IIIB, Non-Small Cell Lung Cancer
Started Jun 2027
16 enrolled
Lung Non-Squamous Non-Small Cell Carcinoma
Golcadomide With Pemetrexed, Rituximab, and Dexamethasone for Relapsed and Refractory CNS Lymphomas
Started Oct 2026
18 enrolled
Large B-cell LymphomaCentral Nervous System Lymphoma
Study of Pembrolizumab + Pemetrexed + Platinum Chemotherapy With or Without Zoldonrasib as First Line Treatment in Metastatic Non-squamous RAS G12D-Mutated NSCLC
Started Aug 2026
430 enrolled
NSCLCNon-small Cell Lung CancerNon-Small Cell Lung Cancer NSCLC+4 more
Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)
Started Nov 2025
500 enrolled
Non-Small Cell Lung Cancer
A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer
Started Oct 2025
600 enrolled
Non-Small Cell Lung CancerKRAS G12C Lung Cancer
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.