PEMAZYRE

Peak

pemigatinib

NDAORALTABLETPriority Review
Approved
Apr 2020
Lifecycle
Peak
Competitive Pressure
0/100
Clinical Trials
20

Mechanism of Action

Kinase Inhibitors

Pharmacologic Class:

Kinase Inhibitor

Clinical Trials (5)

NCT07434843Phase 2Not Yet Recruiting

PH 2 Pemigatinib in SDH-deficient GIST

Started Jun 2026
24 enrolled
SDH Gene MutationGastrointestinal Stromal Tumor
NCT06728410Phase 2Recruiting

A Phase II Study of Pemigatinib Plus Durvalumab in Previously Treated Advanced Intrahepatic Cholangiocarcinoma Patients With FGFR-2 Fusion or Rearrangement

Started Jan 2026
38 enrolled
Intrahepatic CholangiocarcinomaFGFR2 Gene RearrangementFGFR2 Gene Mutation
NCT06300528Phase 2Recruiting

Pemigatinib in Patients With Relapsed or Refractory B-cell Non-Hodgkin Lymphomas

Started Oct 2025
27 enrolled
Relapsed or Refractory B-cell Non-Hodgkin LymphomaMantle Cell LymphomaMarginal Zone Lymphoma
NCT06906562Phase 2Recruiting

A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations

Started Aug 2025
40 enrolled
Advanced Pancreatic CarcinomaMetastatic Pancreatic CarcinomaStage II Pancreatic Cancer AJCC v8+2 more
NCT06653777Phase 2Recruiting

Efficacy of Pemigatinib in Patients With Solid Tumors Characterized by an Alteration of the Gene FGFR in Tumor Cells

Started Mar 2025
40 enrolled
Solid Tumor, Miscellaneous

Loss of Exclusivity

LOE Date
Aug 30, 2040
176 months away
Patent Expiry
Aug 30, 2040
Exclusivity Expiry
Aug 26, 2029

Patent Records (4)

Patent #ExpiryTypeUse Code
10131667
Apr 17, 2034
U-2809
9611267
Jan 30, 2035
SubstanceProduct
11466004
May 3, 2039
U-3466
11628162
Aug 30, 2040
U-3571